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Corpus Callosotomy for Intractable Seizures in the Pediatric Age Group
Arch Neurol 48:364-372, Nordgren,R.E.,et al, 1991
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Article Abstract
The results of corpus callostomy in 18 patients 16 years old and younger are presented.Eighty-three percent of our patients have had a significant improvement from the surgery(a decrease in seizure frequency of greater than 80%or no longer having generalized atonic,tonic,or tonic-clonic seizures).The procedure seems to be well tolerated in young patients,and we have not noted a postoperative deterioration in behavior,memory,or language function in our patients.One of our patients died in status epilepticus 3 months after surgery.Nevertheless,we have not encountered any serious morbidity in our other patients.Corpus callostomy can be considered for children with intractable seizures,especially when generalized atonic,tonic,or tonic-clonic(whether primary or secondary) seizures are the major seizure type.
 
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